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M94A0276.TXT
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1994-10-08
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Document 0276
DOCN M94A0276
TI The AIDS epidemic.
DT 9412
AU Conant MA; Department of Dermatology, University of California, San;
Francisco.
SO J Am Acad Dermatol. 1994 Sep;31(3 Pt 2):S47-50. Unique Identifier :
AIDSLINE MED/94358248
AB The nature of the clinical presentation of HIV infection continues to
evolve over time. New cutaneous (e.g., seborrheic dermatitis,
onychomycosis, and tinea pedis) and systemic (e.g., Aspergillus
fumigatus and Penicillium marneffei) opportunistic fungal infections can
now be added to the classic clinical markers for progressive HIV
infection, such as Kaposi's sarcoma, Pneumocystis carinii pneumonia,
Mycobacterium avium intercellulare infections, and cryptococcal
meningitis. The fact that the appearance of many of these fungal
diseases is directly correlated with the patient's CD4 cell count is a
valuable tool for ongoing clinical evaluation. Although systemic
manifestations characterize a progression from asymptomatic HIV
infection to AIDS, many of the signs of disease progression are
cutaneous. Prophylaxis against many of the potentially life-threatening
systemic opportunistic infections associated with HIV positivity has had
a positive impact on the life expectancy of patients with AIDS.
DE Acquired Immunodeficiency Syndrome/COMPLICATIONS/DRUG THERAPY/
*EPIDEMIOLOGY/IMMUNOLOGY Antifungal Agents/THERAPEUTIC USE
AIDS-Related Opportunistic Infections/COMPLICATIONS/DRUG THERAPY/
*EPIDEMIOLOGY Dermatomycoses/COMPLICATIONS/DRUG THERAPY/*EPIDEMIOLOGY/
IMMUNOLOGY Dermatophytes/PATHOGENICITY
Eosinophilia/COMPLICATIONS/*EPIDEMIOLOGY/IMMUNOLOGY
Folliculitis/COMPLICATIONS/*EPIDEMIOLOGY/IMMUNOLOGY Human Incidence
Leukocyte Count T4 Lymphocytes/IMMUNOLOGY JOURNAL ARTICLE REVIEW
REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).